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Cognitive Changes After Adjuvant Treatment in Older Adults with Early-Stage Breast Cancer.


ABSTRACT:

Background

Group-based trajectory modeling is particularly important to identify subgroups of patients with pathological cognitive changes after cancer treatment. To date, only one study has explored cognitive trajectories in older patients with cancer. The present article describes objective cognitive changes before to after adjuvant treatment in older adults with early-stage breast cancer (EBC) after adjuvant treatment compared with healthy controls.

Patients and methods

Participants were patients ≥65 years of age with newly diagnosed EBC and healthy controls (age-, sex-, and education-matched). The pretreatment assessment was conducted before adjuvant therapy, and the post-treatment assessment after the end of the first adjuvant treatment. Objective cognitive changes befo

SUBMITTER: Lange M 

PROVIDER: S-EPMC6324624 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature