Update on the pathophysiology of cluster headache: imaging and neuropeptide studies.

ABSTRACT:

Objective

Cluster headache (CH) is the most severe primary headache condition. Its pathophysiology is multifaceted and incompletely understood. This review brings together the latest neuroimaging and neuropeptide evidence on the pathophysiology of CH.

Methods

A review of the literature was conducted by searching PubMed and Web of Science. The search was conducted using the following keywords: imaging studies, voxel-based morphometry, diffusion-tensor imaging, diffusion magnetic resonance imaging, tractography, connectivity, cerebral networks, neuromodulation, central modulation, deep brain stimulation, orexin-A, orexin-B, tract-based spatial statistics, single-photon emission computer tomography studies, positron-emission tomography, functional magnetic resonance imaging, ma

SUBMITTER: Buture A 

PROVIDER: S-EPMC6324919 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature