Exposure to Trace Elements and Risk of Skin Cancer: A Systematic Review of Epidemiologic Studies.

ABSTRACT: Exposure to environmental trace elements has been studied in relation to many cancers. However, an association between exposure to trace elements and skin cancer remains less understood. Therefore, we conducted a systematic review of published epidemiologic literature examining the association between exposure to trace elements, and risk of melanoma and keratinocyte carcinoma in humans. We identified epidemiologic studies investigating exposure to arsenic, cadmium, chromium, copper, iron, selenium, and zinc and risk of skin cancer in humans. Among the minerals, arsenic, selenium, and zinc had more than five studies available. Exposure to arsenic was associated with increased risk of keratinocyte carcinoma, while too few studies existed on melanoma to draw conclusions. Exposure to selenium

SUBMITTER: Matthews NH 

PROVIDER: S-EPMC6324965 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature