Childhood Overweight, Tallness, and Growth Increase Risks of Ovarian Cancer.

ABSTRACT:

Background

Adult body size is related to ovarian cancer risks, but size in childhood may also influence risks. We investigated if childhood body mass index (kg/m²), height, and growth patterns were associated with ovarian cancer overall and by histologic subtypes, including effects of birthweight.

Methods

A cohort of 155,958 girls from the Copenhagen School Health Records Register, born 1930 to 1989 with measured weights and heights from 7 to 13 years, were included. During follow-up, 1,041 ovarian cancers were recorded. Overweight was defined using International Obesity Task Force criteria. Cox regressions were performed.

Results

Compared with non-overweight girls, at most ages girls with overweight had increased risks of ovarian cancer overall (HR range:

SUBMITTER: Aarestrup J 

PROVIDER: S-EPMC6325003 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature