Adult Physical Activity and Breast Cancer Risk in Women with a Family History of Breast Cancer.

ABSTRACT:

Background

Recreational physical activity has been consistently associated with reduced breast cancer risk. Less is known about how family history of breast cancer affects the association and whether it varies by menopausal status.

Methods

The Sister Study is a cohort of 50,884 women who had a sister with breast cancer but no prior breast cancer themselves at enrollment. Women reported all recreational sport/exercise activities they participated in over the past 12 months. Hours/week and MET-hours/week of physical activity were considered in association with breast cancer risk. Hazard ratios (HR) and 95% confidence intervals (CI) were calculated with Cox regression. Extent of family history, examined as a modifier, was characterized by a Bayesian score incorporating characte

SUBMITTER: Niehoff NM 

PROVIDER: S-EPMC6325010 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature