Uptake and safety of Hepatitis B vaccination during pregnancy: A Vaccine Safety Datalink study.

ABSTRACT:

Introduction

Hepatitis B virus (HBV) infection acquired during pregnancy can pose a risk to the infant at birth that can lead to significant and lifelong morbidity. Hepatitis B vaccine (HepB) is recommended for anyone at increased risk for contracting HBV infection, including pregnant women. Limited data are available on the safety of HepB administration during pregnancy.

Objectives

To assess the frequency of maternal HepB receipt among pregnant women and evaluate the potential association between maternal vaccination and pre-specified maternal and infant safety outcomes.

Methods

We examined a retrospective cohort of pregnancies in the Vaccine Safety Datalink (VSD) resulting in live birth outcomes from 2004 through 2015. Eligible pregnancies in women aged 12-55 years

SUBMITTER: Groom HC 

PROVIDER: S-EPMC6325631 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature