Medaka Population Genome Structure and Demographic History Described via Genotyping-by-Sequencing.

ABSTRACT: Medaka is a model organism in medicine, genetics, developmental biology and population genetics. Lab stocks composed of more than 100 local wild populations are available for research in these fields. Thus, medaka represents a potentially excellent bioresource for screening disease-risk- and adaptation-related genes in genome-wide association studies. Although the genetic population structure should be known before performing such an analysis, a comprehensive study on the genome-wide diversity of wild medaka populations has not been performed. Here, we performed genotyping-by-sequencing (GBS) for 81 and 12 medakas captured from a bioresource and the wild, respectively. Based on the GBS data, we evaluated the genetic population structure and estimated the demographic parameters using an app

SUBMITTER: Katsumura T 

PROVIDER: S-EPMC6325896 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature