The PathLink Acquired Gestational Tissue Bank: Feasibility of Project PLACENTA.

ABSTRACT:

Background

The Vanderbilt Institute for Clinical and Translational Research piloted the development of Project PLACENTA (PathLink Acquired gEstatioNal Tissue bAnk). This project investigated the feasibility of a fresh gestational tissue biobank, which provides tissue linked to electronic medical records for investigators interested in maternal-fetal health.

Methods

We developed a pipeline for collection of placental tissue from Labor and Delivery within approximately 30 minutes of delivery. An email alert was developed, to signal delivery, with the ability to specifically flag patients with certain phenotypic traits. Once collected, 4 to 8 mm punch biopsy cores were snap frozen and subsequently used for DNA, RNA and protein extraction. Tissue was also collected for Formalin

SUBMITTER: Linder JE 

PROVIDER: S-EPMC6326187 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature