Diabetes mellitus and the risk of fractures at specific sites: a meta-analysis.

ABSTRACT:

Objective

Diabetes mellitus (DM) is associated with an increased fracture risk; however, the impact of DM and subsequent fracture at different sites and the associations according to patient characteristics remain unknown.

Design

Meta-analysis DATA SOURCES: The PubMed, EMBASE and Cochrane Library databases were searched from inception to March 2018.

Eligibility criteria

We included prospective and retrospective cohort studies on the associations of DM and subsequent fracture risk at different sites.

Data extraction and synthesis

Two authors independently extracted data and assessed the study quality. Relative risks (RRs) with 95% CIs were calculated using a random-effects model, and the heterogeneity across the included studies was evaluated using I²

SUBMITTER: Wang H 

PROVIDER: S-EPMC6326306 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature