Long-term tolerability and effectiveness of raltegravir in Japanese patients: Results from post-marketing surveillance.

ABSTRACT: Antiretroviral agents are approved in Japan based on non-clinical and clinical data reported from overseas. Neither the long-term tolerability nor the effectiveness of raltegravir or other integrase strand transfer inhibitors in Japan is known. This study reports on the long-term tolerability and effectiveness of raltegravir in Japanese clinical practice using data collected through approximately 9 years of post-marketing surveillance. This observational survey used data on human immunodeficiency virus (HIV) infected patients initiated treatment with raltegravir between 2008 and 2017 in the HIV-related drug (HRD) cooperative survey to assess the safety and effectiveness of raltegravir in real world clinical practice. There were totally 1,303 patients prescribed raltegravir across 30 instit

SUBMITTER: Kuroishi N 

PROVIDER: S-EPMC6326570 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature