Fine-scale spatial and temporal dynamics of kdr haplotypes in Aedes aegypti from Mexico.

ABSTRACT:

Background

As resistance to insecticides increases in disease vectors, it has become exceedingly important to monitor populations for susceptibility. Most studies of field populations of Aedes aegypti have largely characterized resistance patterns at the spatial scale of the city or country, which may not be completely informative given that insecticide application occurs at the scale of the house or city block. Phenotypic resistance to pyrethroids dominates in Ae. aegypti, and it has been partially explained by mutations in the voltage-gated sodium channel gene. Here, we assess community-level patterns of four knockdown resistance (kdr) haplotypes (C1534/I1016, F1534/I1016, C1534/V1016 and F1534/V1016) in Ae. aegypti in 24 randomly chosen city blocks from a city in Yucatán State,

SUBMITTER: Grossman MK 

PROVIDER: S-EPMC6327429 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature