Significant association between joint ultrasonographic parameters and synovial inflammatory factors in rheumatoid arthritis.

ABSTRACT:

Background

Ultrasonography (US) can directly demonstrate joint inflammation, including grayscale (GS) signs of synovial hypertrophy and power Doppler (PD) techniques to demonstrate increased blood flow and vascularization. Recently, echogenicity, especially hypoechoic synovium, has also been associated with local inflammatory activity. However, only a few studies have demonstrated correlation between histopathologic and immunopathologic evaluation and US findings. The aim of this study was to clarify whether joint US findings including synovial hypertrophy, vascularity, and echogenicity can accurately characterize synovial pathophysiology in patients with active rheumatoid arthritis (RA).

Methods

A total of 44 patients with RA were included, both treated (n = 25) and untreat

SUBMITTER: Kondo Y 

PROVIDER: S-EPMC6327469 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature