Development of an agent-based model to assess the impact of substandard and falsified anti-malarials: Uganda case study.

ABSTRACT:

Background

Global efforts to address the burden of malaria have stagnated in recent years with malaria cases beginning to rise. Substandard and falsified anti-malarial treatments contribute to this stagnation. Poor quality anti-malarials directly affect health outcomes by increasing malaria morbidity and mortality, as well as threaten the effectiveness of treatment by contributing to artemisinin resistance. Research to assess the scope and impact of poor quality anti-malarials is essential to raise awareness and allocate resources to improve the quality of treatment. A probabilistic agent-based model was developed to provide country-specific estimates of the health and economic impact of poor quality anti-malarials on paediatric malaria. This paper presents the methodology and case

SUBMITTER: Ozawa S 

PROVIDER: S-EPMC6327614 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature