Cardioplegia in paediatric cardiac surgery: a systematic review of randomized controlled trials.

ABSTRACT:

Objectives

Cardioplegia is the primary method for myocardial protection during cardiac surgery. We conducted a systematic review of randomized controlled trials of cardioplegia in children to evaluate the current evidence base.

Methods

We searched MEDLINE, CENTRAL and LILACS and manually screened retrieved references and systematic reviews to identify all randomized controlled trials comparing cardioplegia solutions or additives in children undergoing cardiac surgery published in any language; secondary publications and those reporting inseparable adult data were excluded. Two or more reviewers independently screened studies for eligibility and extracted data; the Cochrane Risk of Bias tool was used to assess for potential biases.

Results

We identified 26 trials rando

SUBMITTER: Drury NE 

PROVIDER: S-EPMC6328004 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature