Delayed differentiation of vaginal and uterine microbiomes in dairy cows developing postpartum endometritis.

ABSTRACT: Bacterial overgrowth in the uterus is a normal event after parturition. In contrast to the healthy cow, animals unable to control the infection within 21 days after calving develop postpartum endometritis. Studies on the Microbial Ecology of the bovine reproductive tract have focused on either vaginal or uterine microbiomes. This is the first study that compares both microbiomes in the same animals. Terminal Restriction Fragment Length Polymorphism of the 16S rRNA gene showed that despite large differences associated to individuals, a shared community exist in vagina and uterus during the postpartum period. The largest changes associated with development of endometritis were observed at 7 days postpartum, a time when vaginal and uterine microbiomes were most similar. 16S rRNA pyrosequencin

SUBMITTER: Miranda-CasoLuengo R 

PROVIDER: S-EPMC6328119 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature