Characterizing active transportation mechanisms for free fatty acids and antibiotics in Synechocystis sp. PCC 6803.

ABSTRACT:

Background

Synechocystis sp. PCC 6803 is a photosynthetic bacterium that has been genetically modified to produce industrially relevant chemicals, yet efflux mechanisms have not been well elucidated. These photosynthetic organisms live in environments that are often nutrient limited; therefore, the genome of these organisms encodes far fewer proteins used for efflux of chemicals when compared to members of the Enterobacteriaceae family. Understanding efflux mechanisms can lead to a greater efficiency of chemical production within the cyanobacterial cell.

Results

Both sll0180 and slr2131 genes that encode the Sll0180 and Slr2131 proteins, respectively, were removed from Synechocystis sp. PCC 6803 and SD277, a high fatty acid-producing Synechocystis-based strain, to test the h

SUBMITTER: Bellefleur MPA 

PROVIDER: S-EPMC6329066 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature