Quality of life and utility decrement associated with Clostridium difficile infection in a French hospital setting.

ABSTRACT:

Background

Clostridium difficile infection (CDI) is associated with a substantial Quality of life impact on patients that has not been so far measured with a generic validated instrument.

Methods

A prospective study was performed in 7 French acute-care settings in patients presenting with a bacteriologically-confirmed CDI. The EQ-5D-3 L was filled in by patients at 7 ± 2 days after CDI diagnosis to describe their state of health at that date as well as their state of health immediately before the CDI episode (baseline). Individual utility decrement was obtained by subtracting the corresponding utilities. The Quality Adjusted Life Year (QALY) loss was calculated by multiplying the days spent from baseline to the date of the interview, by the decrement of utility. A multivaria

SUBMITTER: Barbut F 

PROVIDER: S-EPMC6329091 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature