Early diuretic use and mortality in critically ill patients with vasopressor support: a propensity score-matching analysis.

ABSTRACT:

Background

The effect of loop diuretic use in critically ill patients on vasopressor support or in shock is unclear. This study aimed to explore the relationship between loop diuretic use and hospital mortality in critically ill patients with vasopressor support.

Methods

Data were extracted from the Medical Information Mart for Intensive Care III database. Adult patients with records of vasopressor use within 48 h after intensive care unit admission were screened. Multivariable logistic regression and propensity score matching was used to investigate any association.

Results

Data on 7828 patients were included. The crude hospital mortality was significantly lower in patients with diuretic use (166/1469 vs. 1171/6359, p <  0.001). In the extended multivariable logistic

SUBMITTER: Shen Y 

PROVIDER: S-EPMC6329160 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature