Catch-up growth, metabolic, and cardiovascular risk in post-institutionalized Romanian adolescents.

ABSTRACT:

Background

Reduced prenatal growth followed by rapid postnatal weight gain are risk factors for developing metabolic and cardiovascular disease. Children reared in institutions experience a similar pattern of growth restriction followed by catch-up growth after removal. We explored whether patterns of catch-up growth affect metabolic and cardiovascular outcomes in previously institutionalized adolescents.

Method

A longitudinal study of institutionalized infants randomized to care as usual (n = 68) or foster care intervention (n = 68), and never institutionalized controls (n = 127). Body mass index (BMI) was measured at baseline (20 months), 30, 42 months, and ages 8, 12, 16. At age 16, metabolic and pro-inflammatory markers were derived from blood samples.

Results

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SUBMITTER: Tang A 

PROVIDER: S-EPMC6330119 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature