Ontology highlight
ABSTRACT:
SUBMITTER: Hao S
PROVIDER: S-EPMC6330278 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Hao Sicheng S Wang Rui R Zhang Yu Y Zhan Hui H
Frontiers in genetics 20190107
Alzheimer's disease (AD) is the most common cause of dementia. It is the fifth leading cause of death among elderly people. With high genetic heritability (79%), finding the disease's causal genes is a crucial step in finding a treatment for AD. Following the International Genomics of Alzheimer's Project (IGAP), many disease-associated genes have been identified; however, we do not have enough knowledge about how those disease-associated genes affect gene expression and disease-related pathways. ...[more]