Prenatal Exposure to Traffic Pollution and Childhood Body Mass Index Trajectory.

ABSTRACT: Background: Limited evidence suggests an association between prenatal exposure to traffic pollution and greater adiposity in childhood, but the time window during which growth may be most affected is not known. Methods: We studied 1,649 children in Project Viva, a Boston-area pre-birth cohort. We used spatiotemporal models to estimate prenatal residential air pollution exposures and geographic information systems to estimate neighborhood traffic density and roadway proximity. We used weight and stature measurements at clinical and research visits to estimate a BMI trajectory for each child with mixed-effects natural cubic spline models. In primary analyses, we examined associations of residential PM_2.5 and black carbon (BC) exposures during the third trimester and

SUBMITTER: Fleisch AF 

PROVIDER: S-EPMC6330299 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature