Genetic diversity of the Yokose virus, XYBX1332, isolated from bats (Myotis daubentonii) in China.

ABSTRACT:

Background

Yokose virus was first isolated from bats (Miniopterus fuliginosus) collected in Yokosuka, Japan, in 1971, and is a new member of the family Flaviviridae, genus Flavivirus. In this study, we isolated a Yokose virus from a serum sample of Myotis daubentonii (order Chiroptera, family Vespertilionidae) collected in Yunnan province, China in 2013.

Methods

The serum specimens of bat were used to inoculate in BHK-21 and Vero E6 cells for virus isolation. Then the viral complete genome sequence was obtained and was used for phylogenetic analysis performed by BEAST software package.

Results

The virus was shown to have cytopathic effects in mammalian cells (BHK-21 and Vero E6). Genome sequencing indicated that it has a single open reading frame (ORF), with a genome

SUBMITTER: Feng Y 

PROVIDER: S-EPMC6330390 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature