Vaccination Guidelines for Patients With Immune-Mediated Disorders on Immunosuppressive Therapies.

ABSTRACT:

Background:

Patients with immune-mediated diseases on immunosuppressive therapies have more infectious episodes than healthy individuals, yet vaccination practices by physicians for this patient population remain suboptimal.

Objectives:

To evaluate the safety and efficacy of vaccines in individuals exposed to immunosuppressive therapies and provide evidence-based clinical practice recommendations.

Methods:

A literature search for vaccination safety and efficacy in patients on immunosuppressive therapies (2009-2017) was conducted. Results were assessed using the Grading of Recommendation, Assessment, Development, and Evaluation system.

Results:

Several immunosuppressive therapies attenuate vaccine response. Thus, vaccines should be administered before treatment

SUBMITTER: Papp KA 

PROVIDER: S-EPMC6330697 | biostudies-literature | 2019 Jan/Feb

REPOSITORIES: biostudies-literature