Follow-up study of high-dose praziquantel therapy for cerebral sparganosis.

ABSTRACT:

Background

Cerebral sparganosis is the most serious complication of human sparganosis. Currently, there is no standard for the treatment of inoperable patients. Conventional-dose praziquantel therapy is the most reported treatment. However, the therapeutic outcomes are not very effective. High-dose praziquantel therapy is a useful therapeutic choice for many parasitic diseases that is well tolerated by patients, but it has not been sufficiently evaluated for cerebral sparganosis. This study aims to observe the prognoses following high-dose praziquantel therapy in inoperable patients and the roles of MRI and peripheral eosinophil absolute counts during follow-up.

Methodology

Baseline and follow-up epidemiological, clinical, radiological and therapeutic data related to 10 inop

SUBMITTER: Zhang P 

PROVIDER: S-EPMC6331082 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature