HIV-Related Stigma, Motivation to Adhere to Antiretroviral Therapy, and Medication Adherence Among HIV-Positive Methadone-Maintained Patients.

ABSTRACT:

Background

Opioid agonist therapies with methadone are associated with higher levels of adherence to antiretroviral therapy (ART); yet, no studies have explored factors associated with optimal ART levels in HIV-positive patients on methadone maintenance treatment, including explanatory pathways using mediation analysis.

Setting

Participants included 121 HIV-positive, methadone-maintained patients who reported HIV-risk behaviors and were taking ART.

Methods

Participants were assessed using an audio computer-assisted self-interview. Multivariable logistic regression was used to identify significant correlates and PROCESS macro to test the explanatory pathway (ie, mediational effect) for optimal ART adherence.

Results

Among 121 participants, almost 40% reported su

SUBMITTER: Shrestha R 

PROVIDER: S-EPMC6331231 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature