The Protective Effects of Ciji-Hua'ai-Baosheng II Formula on Chemotherapy-Treated H₂₂ Hepatocellular Carcinoma Mouse Model by Promoting Tumor Apoptosis.

ABSTRACT: Ciji-Hua'ai-Baosheng II Formula (CHB-II-F) is a traditional Chinese medical formula that has been shown in clinical practice to relieve side effects of chemotherapy and improve quality of life for cancer patients. In order to understand the mechanism of its protective effects on chemotherapy, mice with transplanted H₂₂ hepatocellular carcinoma were employed in this study. Ninety-two mice were injected subcutaneously with H₂₂ HCC cell suspension into the right anterior armpit. After mice were treated with 5-fluorine pyrimidine (5-FU), they were divided into six groups as untreated group, 5-FU group, 5-FU plus Yangzheng Xiaoji Capsule group and three groups of 5-FU plus different concentrations of CHB-II-F. Twenty mice were euthanized after 7 days of treatment in untrea

SUBMITTER: Fu B 

PROVIDER: S-EPMC6331466 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature