Impact of intraoperative stimulation mapping on high-grade glioma surgery outcome: a meta-analysis.

ABSTRACT:

Background

Intraoperative stimulation mapping (ISM) using electrocortical mapping (awake craniotomy, AC) or evoked potentials has become a solid option for the resection of supratentorial low-grade gliomas in eloquent areas, but not as much for high-grade gliomas. This meta-analysis aims to determine whether the surgeon, when using ISM and AC, is able to achieve improved overall survival and decreased neurological morbidity in patients with high-grade glioma as compared to resection under general anesthesia (GA).

Methods

A systematic search was performed to identify relevant studies. Adult patients were included who had undergone craniotomy for high-grade glioma (WHO grade III or IV) using ISM (among which AC) or GA. Primary outcomes were rate of postoperative complications,

SUBMITTER: Gerritsen JKW 

PROVIDER: S-EPMC6331492 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature