Affective problems and decline in cognitive state in older adults: a systematic review and meta-analysis.

ABSTRACT: Evidence suggests that affective problems, such as depression and anxiety, increase risk for late-life dementia. However, the extent to which affective problems influence cognitive decline, even many years prior to clinical diagnosis of dementia, is not clear. The present study systematically reviews and synthesises the evidence for the association between affective problems and decline in cognitive state (i.e., decline in non-specific cognitive function) in older adults. An electronic search of PubMed, PsycInfo, Cochrane, and ScienceDirect was conducted to identify studies of the association between depression and anxiety separately and decline in cognitive state. Key inclusion criteria were prospective, longitudinal designs with a minimum follow-up period of 1 year. Data extraction and m

SUBMITTER: John A 

PROVIDER: S-EPMC6331688 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature