Association of Periodontal Disease and Edentulism With Hypertension Risk in Postmenopausal Women.

ABSTRACT:

Background

Multiple cross-sectional epidemiologic studies have suggested an association between periodontal disease and tooth loss and hypertension, but the temporality of these associations remains unclear. The objective of our study was to evaluate the association of baseline self-reported periodontal disease and edentulism with incident hypertension.

Methods

Study participants were 36,692 postmenopausal women in the Women's Health Initiative-Observational Study who were followed annually from initial periodontal assessment (1998-2003) through 2015 (mean follow-up 8.3 years) for newly diagnosed treated hypertension. Cox proportional hazards regression with adjustment for potential confounders was used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs).

SUBMITTER: Gordon JH 

PROVIDER: S-EPMC6331709 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature