Heart-to-Brachium Pulse Wave Velocity as a Measure of Proximal Aortic Stiffness: MRI and Longitudinal Studies.

ABSTRACT:

Background

Stiffening of the proximal aorta is associated with heightened cardiovascular disease risks but can be quantified by limited methodologies (e.g., magnetic resonance imaging [MRI]). As an initial step to evaluate the emerging technique to assess proximal aortic stiffness via pulse wave velocity from the heart to the brachium (hbPWV), we determined the influences of aging on pulse wave velocity (PWV) and aortic hemodynamics.

Method

Using the cross-sectional and follow-up study designs, hbPWV was compared and evaluated in relation to other PWV in various arterial segments. Arterial path lengths were measured by the 3-dimensional arterial tracing of MRI.

Results

In the cross-sectional study including 190 subjects (aged 19-79 years), hbPWV exhibited one of the l

SUBMITTER: Sugawara J 

PROVIDER: S-EPMC6331710 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature