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The Biosynthetic Pathways of Tanshinones and Phenolic Acids in Salvia miltiorrhiza.


ABSTRACT: Secondary metabolites from plants play key roles in human medicine and chemical industries. Due to limited accumulation of secondary metabolites in plants and their important roles, characterization of key enzymes involved in biosynthetic pathway will enable metabolic engineering or synthetic biology to improve or produce the compounds in plants or microorganisms, which provides an alternative for production of these valuable compounds. Salvia miltiorrhiza, containing tanshinones and phenolic acids as its active compounds, has been widely used for the treatment of cardiovascular and cerebrovascular diseases. The biosynthetic analysis of secondary metabolites in S. miltiorrhiza has made great progress due to the successful genetic transformation system, simplified hairy roots system, and hi

SUBMITTER: Ma XH 

PROVIDER: S-EPMC6332233 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature