Futile reperfusion and predicted therapeutic benefits after successful endovascular treatment according to initial stroke severity.

ABSTRACT:

Background

Futile reperfusion (poor functional status despite successful reperfusion) was observed in up to 67% of patients enrolled in recent endovascular treatment (EVT) clinical trials. We investigated the impact of baseline stroke severity on both futile reperfusion and therapeutic benefit of successful EVT.

Methods

Using a prospective multicenter stroke registry, we identified consecutive ischemic stroke patients with anterior circulation large artery occlusion, who were reperfused successfully by EVT (Thrombolysis in Cerebral Infarction grade 2b-3). The rate of futile reperfusion was assessed across the initial National Institutes of Health Stroke Scale (NIHSS) scores. The frequency of poor outcomes (modified Rankin scale [mRS] 3-6) according to NIHSS scores was compar

SUBMITTER: Lee SH 

PROVIDER: S-EPMC6332890 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature