Facilitating informed choice about non-invasive prenatal testing (NIPT): a systematic review and qualitative meta-synthesis of women's experiences.

ABSTRACT:

Background

Non-invasive prenatal testing (NIPT) can be used to accurately detect fetal chromosomal anomalies early in pregnancy by assessing cell-free fetal DNA present in maternal blood. The rapid diffusion of NIPT, as well as the ease and simplicity of the test raises concerns around informed decision-making and the potential for routinization. Introducing NIPT in a way that facilitates informed and autonomous decisions is imperative to the ethical application of this technology. We approach this imperative by systematically reviewing and synthesizing primary qualitative research on women's experiences with and preferences for informed decision-making around NIPT.

Methods

We searched multiple bibliographic databases including Ovid MEDLINE, EBSCO Cumulative Index to Nursing

SUBMITTER: Cernat A 

PROVIDER: S-EPMC6332899 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature