Advances in the application of comprehensive two-dimensional gas chromatography in metabolomics.

ABSTRACT: Due to excellent separation capacity for complex mixtures of chemicals, comprehensive two-dimensional gas chromatography (GC × GC) is being utilized with increasing frequency for metabolomics analyses. This review describes recent advances in GC × GC method development for metabolomics, organismal sampling techniques compatible with GC × GC, metabolomic discoveries made using GC × GC, and recommendations and best practices for collecting and reporting GC × GC metabolomics data.

SUBMITTER: Keppler EAH 

PROVIDER: S-EPMC6333419 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature