SMoLR: visualization and analysis of single-molecule localization microscopy data in R.

ABSTRACT:

Background

Single-molecule localization microscopy is a super-resolution microscopy technique that allows for nanoscale determination of the localization and organization of proteins in biological samples. For biological interpretation of the data it is essential to extract quantitative information from the super-resolution data sets. Due to the complexity and size of these data sets flexible and user-friendly software is required.

Results

We developed SMoLR (Single Molecule Localization in R): a flexible framework that enables exploration and analysis of single-molecule localization data within the R programming environment. SMoLR is a package aimed at extracting, visualizing and analyzing quantitative information from localization data obtained by single-molecule microscop

SUBMITTER: Paul MW 

PROVIDER: S-EPMC6334411 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature