Association of G-protein coupled purinergic receptor P2Y2 with ischemic stroke in a Han Chinese population of North China.

ABSTRACT: The G-protein-coupled purinergic receptor P2Y2 (P2RY2) plays an important role in the mechanism of atherosclerosis, which is relevant to ischemic stroke. This retrospective case-control study aimed to assess the relationship between P2RY2 gene polymorphisms and ischemic stroke risk in the northern Han Chinese population. In this study, clinical data and peripheral blood specimens were collected from 378 ischemic stroke patients and 344 controls. The ischemic stroke participants were recruited from the First Affiliated Hospital of China Medical University and the First Affiliated Hospital of Liaoning Medical University. The controls were recruited from the Health Check Center at the First Affiliated Hospital of China Medical University. Ischemic stroke patients were divided into two subgrou

SUBMITTER: Yuan LY 

PROVIDER: S-EPMC6334602 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature