NICU management and outcomes of infants with trisomy 21 without major anomalies.

ABSTRACT:

Objective

To describe how trisomy 21 affects neonatal intensive care management and outcomes of full-term infants without congenital anomalies.

Study design

Retrospective cohort of full-term infants without anomalies with and without trisomy 21 admitted to Pediatrix NICUs from 2005 to 2012. We compared diagnoses, management, length of stay, and discharge outcomes.

Results

In all, 4623 infants with trisomy 21 and 606 770 infants without trisomy 21 were identified. One-third of infants in the NICU with and without trisomy 21 were full term without major anomalies. Trisomy 21 infants had more respiratory distress, thrombocytopenia, feeding problems, and pulmonary hypertension. They received respiratory support for a longer period of time and had a longer length of stay.<

SUBMITTER: McAndrew S 

PROVIDER: S-EPMC6335104 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature