Adverse effects of small for gestational age differ by gestational week among very preterm infants.

ABSTRACT:

Objective

To characterise the excess risk for death, grade 3-4 intraventricular haemorrhage (IVH), bronchopulmonary dysplasia (BPD) and stage 3-5 retinopathy of prematurity independently associated with birth small for gestational age (SGA) among very preterm infants, stratified by completed weeks of gestation.

Methods

Retrospective cohort study using the Optum Neonatal Database. Study infants were born <32 weeks gestation without severe congenital anomalies. SGA was defined as a birth weight <10th percentile. The excess outcome risk independently associated with SGA birth among SGA babies was assessed using adjusted risk differences (aRDs).

Results

Of 6708 infants sampled from 717 US hospitals, 743 (11.1%) were SGA. SGA compared with non-SGA infants experienced highe

SUBMITTER: Jensen EA 

PROVIDER: S-EPMC6335180 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature