A Single-Cell Level and Connectome-Derived Computational Model of the Drosophila Brain.

ABSTRACT: Computer simulations play an important role in testing hypotheses, integrating knowledge, and providing predictions of neural circuit functions. While considerable effort has been dedicated into simulating primate or rodent brains, the fruit fly (Drosophila melanogaster) is becoming a promising model animal in computational neuroscience for its small brain size, complex cognitive behavior, and abundancy of data available from genes to circuits. Moreover, several Drosophila connectome projects have generated a large number of neuronal images that account for a significant portion of the brain, making a systematic investigation of the whole brain circuit possible. Supported by FlyCircuit (http://www.flycircuit.tw), one of the largest Drosophila neuron image databases, we

SUBMITTER: Huang YC 

PROVIDER: S-EPMC6335393 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature