Hepatic leptospiral infections in dogs without obvious renal involvement.

ABSTRACT:

Background

Reports of chronic hepatitis in dogs caused by Leptospira spp. are confined to small case series. Fluorescence in situ hybridization (FISH) allows the identification of spirochetes in liver samples. Consequently, this technique may help elucidate the role of Leptospira spp. in cases of chronic hepatitis.

Objectives

To describe cases of hepatic leptospirosis in dogs diagnosed by FISH and subsequent polymerase chain reaction (PCR) speciation, with the absence of clinically relevant renal involvement.

Animals

Ten client-owned dogs.

Methods

Retrospective case series from the University of Cambridge presented between 2013 and 2016 or cases consulted by telephone advice during this time period. Cases were selected based on histopathologically confirmed gra

SUBMITTER: McCallum KE 

PROVIDER: S-EPMC6335520 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature