Efficacy of Borrelia burgdorferi vaccine in dogs in North America: A systematic review and meta-analysis.

ABSTRACT:

Background

Lyme borreliosis, a tick-borne disease, is endemic to some parts of North America and is an emerging disease in other parts of the world. Vaccination is an increasingly common, although controversial, method used in the prevention of Lyme disease in dogs; the reported efficacies of Borrelia burgdorferi vaccines in dogs are highly variable, ranging from 50% to 100%.

Objectives

To determine the efficacy of vaccines for prevention of Lyme disease in dogs in North America.

Methods

Experimental and observational study designs were eligible for inclusion. The outcome of interest was the reduction of incidence of clinical illness after exposure to B. burgdorferi. Electronic databases searched were MEDLINE, Web of Science, and Centre for Agricultural Biosciences Ab

SUBMITTER: Vogt NA 

PROVIDER: S-EPMC6335541 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature