Newborn dried blood spot samples in Denmark: the hidden figures of secondary use and research participation.

ABSTRACT: Each year millions of newborns are part of a newborn disease-screening program in which, after initial screening, the newborn dried blood spot (NDBS) samples can be stored and used as a population-based research resource. However, very little knowledge exists about how these samples are used for secondary purposes. Our objective is to estimate and describe the usage of a NDBS-based national population biobank for secondary research purposes. We therefore conducted a scoping study with a literature search for all published articles using samples from the Danish Newborn Screening Biobank. Our main inclusion criteria were that the articles had to have actively used and analyzed one or more of the Danish NDBS samples for a purpose beyond the primary screening. Our search led to a final 104 art

SUBMITTER: Nordfalk F 

PROVIDER: S-EPMC6336790 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature