Identification and In Vivo Characterisation of Cardioactive Peptides in Drosophila melanogaster.

ABSTRACT: Neuropeptides and peptide hormones serve as critical regulators of numerous biological processes, including development, growth, reproduction, physiology, and behaviour. In mammals, peptidergic regulatory systems are complex and often involve multiple peptides that act at different levels and relay to different receptors. To improve the mechanistic understanding of such complex systems, invertebrate models in which evolutionarily conserved peptides and receptors regulate similar biological processes but in a less complex manner have emerged as highly valuable. Drosophila melanogaster represents a favoured model for the characterisation of novel peptidergic signalling events and for evaluating the relevance of those events in vivo. In the present study, we analysed a set of ne

SUBMITTER: Schiemann R 

PROVIDER: S-EPMC6337577 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature