Risk factors for recurrent severe anemia among previously transfused children in Uganda: an age-matched case-control study.

ABSTRACT:

Background

In resource-poor settings, transfused children often experience recurrence of severe anemia (SA) following discharge from hospital. This study determined the factors associated with recurrent severe anemia (RSA) among previously transfused Ugandan children aged less than 5 years.

Methods

A case-control study was conducted in five hospitals in Uganda from March 2017 to September 2018. We prospectively enrolled 196 hospitalised children who had been transfused for severe anemia 2 weeks to 6 months prior to enrollment. Of these, 101 children (cases) were re-admitted with a hemoglobin [Hb] level of ≤6 g/dL and required transfusion; and 95 children (age-matched controls) were admitted for other clinical illness with a Hb > 6 g/dL. Children known to have sickle cell ane

SUBMITTER: Dhabangi A 

PROVIDER: S-EPMC6337863 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature