The Anorexia Nervosa Genetics Initiative (ANGI): Overview and methods.

ABSTRACT:

Background

Genetic factors contribute to anorexia nervosa (AN); and the first genome-wide significant locus has been identified. We describe methods and procedures for the Anorexia Nervosa Genetics Initiative (ANGI), an international collaboration designed to rapidly recruit 13,000 individuals with AN and ancestrally matched controls. We present sample characteristics and the utility of an online eating disorder diagnostic questionnaire suitable for large-scale genetic and population research.

Methods

ANGI recruited from the United States (US), Australia/New Zealand (ANZ), Sweden (SE), and Denmark (DK). Recruitment was via national registers (SE, DK); treatment centers (US, ANZ, SE, DK); and social and traditional media (US, ANZ, SE). All cases had a lifetime AN diagnosis ba

SUBMITTER: Thornton LM 

PROVIDER: S-EPMC6338222 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature