Early childhood depression, emotion regulation, episodic memory, and hippocampal development.

ABSTRACT: Depression in adults is associated with deficits in a number of cognitive domains, however it remains less clear how early in development theses deficits can be detected in early onset depression. There are several different hypotheses about the links between cognitive function and depression. For example, it has been argued that executive function deficits contribute to emotion regulation difficulties, which in turn increase risk for depression. Further, it has been suggested that some cognitive deficits, such as episodic memory, may reflect hippocampal abnormalities linked to both depression and episodic memory. We examined these questions in adolescents participating in a longitudinal study of preschool onset depression. We measured cognitive function at adolescence using the National I

SUBMITTER: Barch DM 

PROVIDER: S-EPMC6338439 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature