Deprescribing interventions and their impact on medication adherence in community-dwelling older adults with polypharmacy: a systematic review.

ABSTRACT:

Background

Polypharmacy, and the associated adverse drug events such as non-adherence to prescriptions, is a common problem for elderly people living with multiple comorbidities. Deprescribing, i.e. the gradual withdrawal from medications with supervision by a healthcare professional, is regarded as a means of reducing adverse effects of multiple medications including non-adherence. This systematic review examines the evidence of deprescribing as an effective strategy for improving medication adherence amongst older, community dwelling adults.

Methods

A mixed methods review was undertaken. Eight bibliographic database and two clinical trials registers were searched between May and December 2017. Results were double screened in accordance with pre-defined inclusion/exclusion

SUBMITTER: Ulley J 

PROVIDER: S-EPMC6339421 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature