Association Between Maternal 2nd Trimester Plasma Folate Levels and Infant Bronchiolitis.

ABSTRACT: Objectives Viral bronchiolitis is the most common cause of infant hospitalization. Folic acid supplementation is important during the periconceptional period to prevent neural tube defects. An area of investigation is whether higher prenatal folate is a risk factor for childhood respiratory illnesses. We investigated the association between maternal 2nd trimester plasma folate levels and infant bronchiolitis. Methods We conducted a retrospective cohort analysis in a subset of mother-infant dyads (n = 676) enrolled in the Conditions Affecting Neurocognitive Development and Learning in Early Childhood study and Tennessee Medicaid. Maternal folate status was determined using 2nd trimester (16-28 weeks) plasma samples. Bronchiolitis diagnosis in the first year of life was ascertained using Int

SUBMITTER: Vereen S 

PROVIDER: S-EPMC6339607 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature