Response in Ambient Low Temperature Plasma Ionization Compared to Electrospray and Atmospheric Pressure Chemical Ionization for Mass Spectrometry.

ABSTRACT: Modern technical evolution made mass spectrometry (MS) an absolute must for analytical chemistry in terms of application range, detection limits and speed. When it comes to mass spectrometric detection, one of the critical steps is to ionize the analyte and bring it into the gas phase. Several ionization techniques were developed for this purpose among which electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) are two of the most frequently applied atmospheric pressure methods to ionize target compounds from liquid matrices or solutions. Moreover, recent efforts in the emerging field of "ambient" MS enable the applicability of newly developed atmospheric pressure techniques to solid matrices, greatly simplifying the analysis of samples with MS and anticipating,

SUBMITTER: Kiontke A 

PROVIDER: S-EPMC6339754 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature