Angiotensin-Converting Enzyme Inhibitors Induce Cough.

ABSTRACT: Angiotensin-converting enzyme inhibitors (ACE-I) are widely used in diseases, such as hypertension, congestive heart failure, and myocardial infarction. Although these drugs are well tolerated, one out of five patients discontinues ACE-I due to drug side effects, mainly chronic cough. However, the pathogenesis of ACE-I-induced cough remains controversial and requires further study. In this review, the mechanisms that are suggested in ACE-I-induced cough pathophysiology will be discussed in detail in light of the current literature.

SUBMITTER: Yılmaz I 

PROVIDER: S-EPMC6340691 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature